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1995-110 – These radiolabeled agents are designed to allow for simple preparation of radioactive markers for measuring colonic transit without the need for an Investigational New Drug application (IND). These radiolabeled agents can be used to evaluate patients with suspected colonic motility disorders.
1995-102 – Detection with the use of broad range primers and the PCR assay for the detection of the WA-1 Agent.
1995-094 – In this system, a low frequency radiation force is exerted point-by-point on the object by a confocal ultrasound transducer. The amplitude of the resulting acoustic field is used to produce a two-dimensional display of the object’s cross sections. This system can produce a high resolution image from an object based on its low frequency (kHz) characteristics.
1995-087 – The base sequence coding for the protein of the human kappa opioid receptor, the deduced amino acid sequence and the cell line transfected with the gene expressing the protein.
1995-055 – Imaging of Tubular Structures; Systems and methods have been developed for imaging tubular structures in the body using 2D and/or 3D.
1995-051 – Sequence analysis has been used to select synthetic peptides for use in the development of rabbit polyclonal antibodies against each of the known human cytosolic sulfotransferase enzymes. These antibodies, in turn, can be used to characterize these enzymes for both research purposes and in the development of drugs that are metabolized by sulfatino in humans.
1994-101 – Technology Description Hospitals and surgery centers face significant cost pressure when it comes to maintaining materials and supplies. With supply costs representing a significant expense in surgical services, close and careful monitoring is needed to reduce costs and improve efficiencies. Developed at Mayo Clinic, the Supply Inventory Management System (SIMS) is a comprehensive program... Read More
1994-072 – The invention provides an isolated and purified human DNA molecule that encodes human estrogen sulfotransferase (EST, SULT1E1). It also provides cell lines and vectors containing human estrogen sulfotransferase DNA that can be used to express the enzyme. The enzyme is useful for screening drugs that are metabolized by human estrogen sulfotransferase.
1993-058 – Open reading frame gene sequence of the neurotensin receptors from human brain tissue.
1993-030 – Human Thiopurine Methyltransferase (TPMT) Gene Discovery - Stably-transformed cells expressing human thiopurine methyltransferase Human Thiopurine Methyltransferase (TPMT) Gene Discovery. Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine, 6-thioguanine and azathioprine. Patent claims to the DNA coding sequence, amino acid sequence and cell lines and mammals in which... Read More
1993-010 – Conditionally Immortalized Human Osteoblastic Cell Line: Normal human bone cells were stably transfected with a gene encoding a temperature-sensitive mutant (tsA58) of SV40 large T antigen; cells proliferate as if immortalized at 33.5C degrees but differentiate at 39.5C degrees; hFOB cells show normal bone cell characteristics with regard to responses to dihydroxyvitamin D3 and PTH, BMP’s,... Read More
1988-049 – HMC-1 is a one-of-a kind human cell line which can serve as a resource for mast cell proteins including granule proteins and mast cell genetic material (DNA and RNA). The HMC-1 line was derived from a patient with mast cell leukemia and we believe it is comprised of immature mast cells. These cells may not respond in all ways as would mature mast cells. HMC-1 cells lack a functional IgE... Read More
1987-046 – Monoclonal Antibody to Bromo-deoxy-uridine. Useful in cell proliferation kits
2006-281 – Time-resolved MRI acquisition methods like TRICKS and BRISK allow for accelerated temporal resolution by acquiring some of the raw data less frequently than a fully sampled method. The proposed method gives a quantitive criterion for which data are most important, and which other data can be skipped with minimal impact. It is shown that for a time-resolved, 3D volume acquisition, up to 70% of... Read More