BET Inhibitors Sensitize Cancer Cells to PARP Inhibitors

Technology #2015-196

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Zhenkun Lou Ph.D.
Min Deng Ph.D.
Managed By
Panya Taysavang
Patent Protection
US Patent Pending

Mayo Clinic has discovered that BET inhibitors hinder the homologous recombination process in DNA repair and that BET inhibitors sensitize tumors to PARP inhibitor treatment.