A Role of USP10 in AMPK Activation and mTOR Inhibition

Technology #2015-066

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Zhenkun Lou Ph.D.
Bo Qin Ph.D.
Min Deng Ph.D.
Managed By
Jon H. Behringer
Patent Protection
US Patent Pending
US Patent Pending

Mayo Clinic has discovered that USP10, an ubiquitin protease, deubinquinates AMPK and inhibits mTOR activity. Activating USP10 could have therapeutic effects in treating diabetes and cancer.