Novel Prodrugs of KATP Channel Openers to Treat Glaucoma

Technology #2013-312

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Michael P. Fautsch Ph.D.
Managed By
Panya Taysavang
Patent Protection
US Patent Pending
US Patent Pending

A series of novel prodrugs of KATP channel openers demonstrated significant intraocular pressure (IOP) lowering in normal mice and in a mouse model of glaucoma. The IOP lowering response obtained from using a KATP channel openers prodrug combined with other glaucoma drugs on the market seems to be somewhat synergistic