A method to quantify tissue mechanical properties in a model-independent way by estimating complex elastic modulus from time-dependant creep response induced by acoustic radiation force. This method uses a formula that converts time-domain creep compliance to frequency domain complex modulus. Then Shearwave Dispersion Ultrasound Vibrometry (SDUV) is used to calibrate the complex modulus so that knowledge of the applied radiation force magnitude is not necessary. Acoustic radiation force creep in combination with shear wave dispersion provides a non-invasive, fast, robust and local measure of tissue mechanical properties without a model.
Acoustic Radiation Force Creep and Shear Wave Dispersion Method for Elasticity ImagingTechnology #2011-224
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