MBP Mouse

Technology #1998-039

Through the use of gene targeting in mouse embryonic stem (ES) cells we have successfully generated a line of mice deficient in eosinophil granule major basic protein-1 (mMBP-1). These mice would be useful in drug discovery programs directed toward developing treatments for asthma, allergy, inflammation and a variety of eosinophil-related disorders.

PMID: 11067904