Through the use of gene targeting in mouse embryonic stem (ES) cells we have successfully generated a line of mice deficient in eosinophil granule major basic protein-1 (mMBP-1). These mice would be useful in drug discovery programs directed toward developing treatments for asthma, allergy, inflammation and a variety of eosinophil-related disorders.
MBP Mouse
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- Categories
- Researchers
- James J. Lee Ph.D.
- Nancy A. Lee Ph.D.
- Managed By
- Giedre Ruzgaite Ph.D.