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2010-032 – A method for producing tissue motion with customized frequency content is described in which push pulses are designed using orthogonal basis functions which then produce desired tissue motion. The push pulses can be a sequence of long duration, in which case motion detection A-lines can be interleaved among the pulses. The result is a more efficient method of making tissue move with optimal... Read More
2010-026 – Accelerated MRI: A method is described for improving parallel acquisition along the longitudinal direction.
2009-375 – Existing systems for positioning a patient for radiation therapy treatment include use of moldable masks (aquaplast) that aid in alignment of bony anatomy and fiducial markers and the tumor target. The current process of aligning the multiple markers can be time consuming and tedious. Gloves are required and the reflective surface coating on the markers is prone to wear out. This invention... Read More
2009-366 – A method and system for producing 3-dimensional ultrasound images of a patient’s breast and also producing planar emission images from a radiopharmaceutical is described. The system allows perfect co-registration of both the ultrasound image and the emission image, thereby allowing comparison of anatomical and functional features of the breast tissue. The system comprises 3 primary components... Read More
2009-315 – Devices and methods for in situ graft fenestration. These concepts are meant to modify aortic stent grafts to allow for placement of branch stent grafts off of the main graft body to cannulate vessels such at the renal arteries. The core concept is to utilize devices placed both within the lumen of the aortic graft and on the outside surface of the aortic graft to create a fenestration... Read More
2009-300 – An endoscopic vessel harvesting device/modification will allow for independent fixation of vessel branches during the harvesting process, and thereby minimizing vessel shrinkage during vessel cauterization. This device/modification will also redirect vessel tension away from the origin of the primary vessel during the harvesting process. This redirection of stress forces along the vessel... Read More
2009-280 – Sonometry is real-time distance measurement between two piezoelectric crystals by the time of flight of an acoustic signal, transmitted by one and received by the other crystal. Three “locator” crystals define a plane. Another “navigator: crystal can be instantaneously spatially located by the distances from the "locator” crystals.
2009-274 – System for Minimally Invasive Local Drug Delivery Local drug delivery is a useful approach to deliver much higher concentrations of a drug to a target site while minimizing systemic side effects. Drug-eluting polymers can be delivered via local injection to deliver drug over an extended period of time. Current systems for local drug delivery have two long-standing challenges: local injections... Read More
2009-202 – Bacterial infection continues to negatively affect outcomes for orthopedic patients despite heightened awareness and increased technologies. Infections at the shoulder may be three times more prevalent than at the knee or hip and is recognized as a considerable clinical problem. The shoulder represents a significant challenge for infection prevention: bacteria contamination of the skin... Read More
Peritrode Minimally Invasive Cirmcumferential Peripheral Nerve Stimulation Electrode, Anchoring System and Placement Assist Device
2009-175 – An eight contact electrode placed “through the needle"via ultrasound visual guidance. The electrode is able to pass under a target nerve and curve over and reside circumferentially around the nerve in a "cuff” configuration thus facilitating efficient pain management.
2009-107 – A device which allows for rapid cleaning of the colon in preparation for colon examination by an endoscope or other imaging methods such as CT or MR colonography. The device is aimed at facilitating colonic lavage to allow either minimal prep, or no prep prior to colonoscopy.
2009-104 – Proximal migration of biliary stents can lead to difficult and time consuming endoscopic removal procedures. Separately, while the use of prophylactic pancreatic stents may be increasing due to potentially decreased risk of pancreatitis, endoscopic procedures are often required to facilitate stent removal. Design features to improve spontaneous stent removal and ease retrieval have been... Read More
2009-095 – Embolization to the head/brain may occur during cardiac catheterization percutaneous intervention of the coronary arteries a treatment of structural heart disease such as percutaneous aortic valve replacement a treatment of paravalvular leak. This has been the result of embolization of atherosclerosis debris. This current device has several iterations. 1) as expandable filter that can be... Read More
2009-055 – Hydogels have wide applications in the biomedical field due to their ability to absorb incredible amounts of aqueous solutions and support cell viability. One particular application hydrogels are being investigated for is nerveguidance conduits to direct and stimulate nerve regeneration by supporting cell growth while simulatanously delivering biologically active molecules. Incorporation of... Read More
2008-380 – A novel electrically conductive polymer composite composed of polycaprolactone fumarate- polypyrrole (PCLF-PPy) for applications in nerve regeneration is disclosed. The synthesis and characterization of PCLF-PPy and in vitro studies showing PCLF-PPy supports both PC12 cell and dorsal root ganglia neurite extension. PCLF-PPy composite materials were synthesized by polymerizing pyrrole in... Read More
2008-348 – Radiation therapy treatment is used in nearly two-thirds of all cancer patients. Accurate targeting of the tumor over the treatment period is critical to effective therapy. Placement of permanent tattoos is the current standard practice to aid in the alignment and targeting of radiation therapy over multiple treatments. Existing tattoo methods involve the use of freehand needle sticks,... Read More
2008-317 – A novel electrically conductive polymer composite composed of polycaprolactone fumarate- polypyrrole (PCLF-PPy) for applications in nerve regeneration is disclosed. The synthesis and characterization of PCLF-PPy and in vitro studies showing PCLF-PPy supports both PC12 cell and dorsal root ganglia neurite extension. PCLF-PPy composite materials were synthesized by polymerizing pyrrole in... Read More
Further Development of System and Method for Overlaying Ultrasound Imagery on a Laparoscopic Camera Display
2008-313 – Software algorithm to fuse images and correct for distortion for overlaying ultrasound imagery on a laparoscopic camera.
2008-292 – Guiding catheters must be of sufficient stiffness to offer support during endovascular procedures, but must not be too stiff to track to their intended target. We describe a system with a relatively supple catheter that has a separate lumens or lumens within its walls, which do not communicate with the main, working lumen. The extra lumens can be used to place stiffening wires after the... Read More
2008-268 – Methods and devices are disclosed for the attachment of a soft tissue structure (e.g., tendon or ligament) to bone or a prosthetic implant. In one form, the device includes a clamp comprising a porous metallic material. The clamp includes a convex tissue engaging surface. The device also includes a fastener for compressing the soft tissue between the tissue engaging surface and the bone or... Read More
2008-279 – When a coronary artery is blocked options include angioplasty (ballooning or stenting across the blockage) or bypass surgery. The most effective means of bypass surgery in terms of long-term results is to use the left internal mammary artery as the bypass vessel. Angioplasty in stenting is frequently not possible when a complete obstruction to a coronary artery is present. Placing the left... Read More
2008-249 – Tendon injuries are very common, but functional restoration of the injured tendon still presents a challenge. Tissue engineering approaches provide the possibility of enhancing tendon healing or tendon tissue regeneration. Mayo Clinic researches have developed an engineered tendon substitute using acellular tendon slices seeded with cultured bone marrow stem cells as a regeneration scaffold... Read More
2008-202 – Balloons are used to create cavities in bones for several applications, including cement injection. Current design features include initial placement of a cannula into the bone, through which the balloon is inserted. An alternative design would be to mount the balloon on the outside of the cannula itself, such that the balloon could simply be inflated once the cannula reaches its intended... Read More
2008-178 – A technique is described for MR imaging of an extended field of which uses a combination of multiple-fixed-station and continuously moving table acquisitions. This preserves the ability to perform acceleration techniques and also provides high time efficiency.
2008-079 – The antibiotic impregnated cement spacer replaces a shoulder arthroplasty that has been removed due to infection. There are several advantages: provides antibiotic release locally, facilitates revision surgery by maintaining joint space, allows for immediate motion, and provides faster recovery. There is only one shoulder spacer in the market, and it does not have a variety of sizes and does... Read More
2008-059 – Clear plastic container used to transport up to 4 (1" square pathology tissue blocks) via suggested method of external transportation from Client site to a pathology lab. This container is designed to ensure that all Surgical Blocks are transported in an easily identifiable and safe manner. A Provisional patent application was filed on July 15, 2008.
2008-100 – The device involves use of high frequency radiation to image simultaneously the mechanical contraction and electro-magnetic field dispersions with higher spatial and temporal resolution than yet realized. This refers to any part of the human body, in particular that cardiovascular system, in order to create a map non-invasively of the local electrophysiology and to determine abnormal areas of... Read More
2008-014 – A fracture fixation system particularly useful for bones of the hand and foot is disclosed. The system uses curved shape-memory alloy (e.g., Nitinol) wires that have a predetermined radius of curvature to accommodate different sized bones. These shape-memory alloy wire forms can be inserted into phalanx, metacarpal or metatarsal bones via a percutaneous technique. The technique uses small... Read More
2007-334 – In accordance with the present invention, there is provided a device (e-pill) and technology for delivery, sensing and monitoring an exercise program that is prescribed by a health worker (or any person interested in health) to a patient (some-one with a disease or propensity for a disease that can be helped by exercise) or any person interested in completing a prescribed program for... Read More
2007-192 – During mapping and ablation of tachyarrhythmias, the ablation catheter is moved around one or more of the cardiac chambers and electrograms are obtained from the tip electrode (usually with respect to a ring electrode situated a few millimeters proximal to the tip electrode) and used to create a map of the cardiac chamber (the map could be a real electro-anatomic map or an abstract one based... Read More
2007-111 – An olecranon fracture fixation system includes an intramedullary core that is dimensioned for insertion in an intramedullary canal of the bone, and a hollow shell that is dimensioned for insertion in the intramedullary canal. The shell includes fixation elements that extend outwardly away from a proximal end of the shell. A fastener is provided for attaching the shell to the core in the... Read More
2006-019 – The invention relates to porous three dimensional structures that may be used to deliver one or more bioactive agents into a location within the body.
2005-327 – There is a need for a technique to minimize or eliminate the flow of current or heat to unintended tissue during radio-frequency ablation (RFA). By forcing the current/heat to flow only through target tissue, higher ablation energies may be used without the risk of perforation or fistulization.
2005-274 – This invention describes a device that slides into the coronary sinus and applies uniform pressure in a stable manner against the limbus.
2005-167 – Chronic obstructive pulmonary disease is a common disorder in which regions of the lung are non-functional or function poorly. One treatment has been surgical resection of non-functioning lung. This invention describes a percutaneous and endoscopic technique that permits the use of ablation between an tranvenous or transarterial catheter and a bronchoscope positioned within the diseased... Read More
2005-136 – This device is used to treat a painful thumb base joint (1st CMC joint) from arthritis. It is composed of three parts: 1) a screw that threads across the wrist bones; 2) a screw that threads into the thumb metacarpal; and, 3) a plastic liner for the ball-and-socket joint formed by the two screws.
2005-115 – Frequently in medical practice there is a need for devices to access tissues that may be difficult to reach. Examples may include: delivery of therapy in the pericardial space outside of the heart (for pacing, defibrillation, placement of medications, or other therapies or energy forms); delivery of treatment for neoplastic or epileptogenic lesions within the brain; or delivery of therapy to... Read More
2005-084 – This invention describes a technique and set of tools used to ablate tissue. In this particular embodiment, the specially-designed electrodes have coiled screw mechanisms. These are inserted into the heart and positioned such that intervening tissue can be subjected to radiofrequency ablation. In this particular embodiment, it can be used to cause tissue necrosis of the basal ventricular... Read More
2005-055 – This implant is a fixation device, shaped in the form of a plate for use in the fixation and stabilization of the thoracolumbar spine. Its design and configuration allow for an anatoic fit of the plate to the spine. Its improved fixation allows it an anatomical and biomechanical advantage in stabilizing thoracolumbar spine trauma both in a primary fashion and/or in conjunction with vertebral... Read More
2004-163 – Composite of porous scaffold with cartilage growth from autologous periosteum chondrogenesis induced by tissue engineering techniques. Biological resurfacing of large osteochondral defects, or a complete joint may be feasible using a porous metal scaffold/autologous periosteal construct. The use of this construct eliminates the necessity of using normal cartilage surface as a donor site and... Read More
2003-119 – A device to facilitate epicardial placement of permanent pacing leads, ablation catheters, and other therapeutic leads/catheters.
2003-090 – Hydrogel microparticles with entrapped liquid are used as the porogen to reproducibly form interconnected pore networks in a porous scaffold. In one embodiment, a biodegradable unsaturated polymer (for example, PPF or PCF), a crosslinking agent (like a free radical initiator), and a porogen comprising biodegradable hydrogel microparticles (such as OPEF) are mixed together and allowed to form... Read More
2003-034 – Mayo Clinic clinicians have created a clear, air - inflatable compression dressing that controls swelling and promotes wound healing.
2002-167 – An RF coil with added coils which transmit only to reduce artifactual signals due to flow or poor magnet shim.
Antibiotic Impregnated Peripherally Inserted Central Catheters (PICC's) with Continuous Central Venous Oximetry
2002-074 – A peripherally inserted central catheter includes three lumens that communicate with its proximal end. A large lumen terminates short of the distal end of the catheter and is used for the infusion of fluids into the venous system. A second lumen terminates at the distal end and is suitable for measuring blood pressure in the central venous system and infusion of fluids into the central venous... Read More
2002-072 – Mayo Clinic researchers have developed a biodegradable polymer device for bridging a gap in a severed nerve. This implant functions both as a scaffold to support axon growth across a gap and as a conduit for the controlled local delivery of agents which may promote axon regeneration.
2002-047 – This is a portable (hand carried), adjustable height, suitcase-style device which stores, in insultated storage compartments, and permits correct anatomic mounting of, harvested porcine upper and lower gastrointestinal tracts on each half of the opened device. This device is intended to demonstrate endoscopic procedures, both diagnostic and therapeutic, using ex vivo animal gastrointestinal... Read More
2002-038 – A synthetic valve/leaflet for manufacturing cardiac valve prostheses - mechanical characteristics include anysotopic elasticity - contains stress-bering fibers and is fitted with a thicker area resembling the Nodule of Arantzius of the mature aortic valves.
2001-087 – Pedicle oblique support pillar system; shares loads applied to pedicle implant in spine fracture fixation; reduces large bending moments, re-deformity, screw loosening, bending, or breakage; also may be utilized in spinal segmental unit fixation and fusion.
2000-155 – Prosthesis with varying stem stiffness from proximal to distal ends; minimizes stress shielding; decreases bone re-sorption adjacent to proximal end of stem.