2012-070 – Extraction of chronically implanted leads from pacemakers and defibrillators is difficult because the leads become scarred into position. Several tools are being developed to separate leads from scar tissue. However, a major challenge is the inability to “grip” or “grab” the lead to apply traction for removal. Proximal traction results in the lead uncoiling, as leads do not accommodate... Read More
2011-111 – Modulating the Autonomic Nervous System to Treat Hypertension and Heart Failure Mayo Clinic physicians have demonstrated that modulation of the autonomic nervous system can reduce blood pressure and improve symptoms in congestive heart failure (CHF) patients. Afferent nerves originating from skeletal muscle or from the kidneys are blocked to achieve the reduction in blood pressure and the... Read More
Transpulmonary Induction of Therapeutic Hypothermia (In Collaboration with Minnesota High-Tech Resources LLC)
2010-284 – Therapeutic hypothermia is a widely accepted methodology for mitigating injury to vital organs following ischemic insults. Cellular metabolism decreases with lower temperatures and this reduction in metabolism protects metabolically active organs including the heart and brain during episodes of ischemia and hypoxia. Therapeutic hypothermia is currently practiced in association with a number... Read More
2010-061 – Calcific aortic valve stenosis is a growing problem in developed countries, and valve replacement surgery is the second most common thoracic surgery performed worldwide (>100,000 procedures performed in the US in 2008). Bioprosthetic valves are the most commonly used devices to replace the stenotic valve, but only have a projected lifespan of 10-12 years. Cells infiltrating the... Read More
2010-054 – Transapical access is being performed increasingly for treatment for a variety of structural heart diseases. In the past, that has been done through a small mini thoracotomy. However, a percutaneous approach is being studied and will be an important means of optimizing and enhancing care of patients. Such a percutaneous transapical approach will need to have a means to percutaneously close... Read More
2009-300 – An endoscopic vessel harvesting device/modification will allow for independent fixation of vessel branches during the harvesting process, and thereby minimizing vessel shrinkage during vessel cauterization. This device/modification will also redirect vessel tension away from the origin of the primary vessel during the harvesting process. This redirection of stress forces along the vessel... Read More
2008-279 – When a coronary artery is blocked options include angioplasty (ballooning or stenting across the blockage) or bypass surgery. The most effective means of bypass surgery in terms of long-term results is to use the left internal mammary artery as the bypass vessel. Angioplasty in stenting is frequently not possible when a complete obstruction to a coronary artery is present. Placing the left... Read More
2008-100 – The device involves use of high frequency radiation to image simultaneously the mechanical contraction and electro-magnetic field dispersions with higher spatial and temporal resolution than yet realized. This refers to any part of the human body, in particular that cardiovascular system, in order to create a map non-invasively of the local electrophysiology and to determine abnormal areas of... Read More
2007-192 – During mapping and ablation of tachyarrhythmias, the ablation catheter is moved around one or more of the cardiac chambers and electrograms are obtained from the tip electrode (usually with respect to a ring electrode situated a few millimeters proximal to the tip electrode) and used to create a map of the cardiac chamber (the map could be a real electro-anatomic map or an abstract one based... Read More
2005-327 – There is a need for a technique to minimize or eliminate the flow of current or heat to unintended tissue during radio-frequency ablation (RFA). By forcing the current/heat to flow only through target tissue, higher ablation energies may be used without the risk of perforation or fistulization.
2005-274 – This invention describes a device that slides into the coronary sinus and applies uniform pressure in a stable manner against the limbus.
2005-115 – Frequently in medical practice there is a need for devices to access tissues that may be difficult to reach. Examples may include: delivery of therapy in the pericardial space outside of the heart (for pacing, defibrillation, placement of medications, or other therapies or energy forms); delivery of treatment for neoplastic or epileptogenic lesions within the brain; or delivery of therapy to... Read More
2005-084 – This invention describes a technique and set of tools used to ablate tissue. In this particular embodiment, the specially-designed electrodes have coiled screw mechanisms. These are inserted into the heart and positioned such that intervening tissue can be subjected to radiofrequency ablation. In this particular embodiment, it can be used to cause tissue necrosis of the basal ventricular... Read More
2003-119 – A device to facilitate epicardial placement of permanent pacing leads, ablation catheters, and other therapeutic leads/catheters.
Antibiotic Impregnated Peripherally Inserted Central Catheters (PICC's) with Continuous Central Venous Oximetry
2002-074 – A peripherally inserted central catheter includes three lumens that communicate with its proximal end. A large lumen terminates short of the distal end of the catheter and is used for the infusion of fluids into the venous system. A second lumen terminates at the distal end and is suitable for measuring blood pressure in the central venous system and infusion of fluids into the central venous... Read More
2002-038 – A synthetic valve/leaflet for manufacturing cardiac valve prostheses - mechanical characteristics include anysotopic elasticity - contains stress-bering fibers and is fitted with a thicker area resembling the Nodule of Arantzius of the mature aortic valves.
1998-060 – A stent that fractures at strategic points to relieve arterial stress after placement.