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2010-038 – The individual cross-sectional images along the arteries were analyzed individually by creating a Region-of-Interest (ROI) that encompassed the vessel wall. To ensure that the entire arterial wall was included into the ROI, the radius of the lumen ® was measured, which was used as the width of the annular ROI surrounding the arterial lumen (12). By creating a binary image of the punctate... Read More
2010-032 – A method for producing tissue motion with customized frequency content is described in which push pulses are designed using orthogonal basis functions which then produce desired tissue motion. The push pulses can be a sequence of long duration, in which case motion detection A-lines can be interleaved among the pulses. The result is a more efficient method of making tissue move with optimal... Read More
2009-235 – Using accelerated time-resolved 3-D imaging methods such as the Mayo-developed Cartesian Acquisition with Projection Reconstruction like sampling (CAPR) it is possible to generate data for both a time series of MR angiograms as well as an image of perfusion.
2009-234 – High Speed serializer/de-serializer (SerDes) paths are rapidly replacing slower local communication paths in digital systems. Engineers must accurately model the SerDes electrical interconnect paths (channels). An important structure used in many channels is loosely described as a “pin-field”. We have developed software which automatically creates these pin-field models for input into... Read More
2009-191 – In MR and CT imaging, any reduction in scan time offers potential benefits ranging from high temporal rate observation of physiologic processes to reduction of motion artifacts to lower radiation dose (for CT) to improve patient comfort and throughput. With compressing sensing (CS) techniques, certain classes of MR and CT images can be accurately reconstructed from highly undersampled (and... Read More
2009-179 – For certain types of time series CT studies, Prior Image Constrained Compressed Sensing (PICCS) has been shown to significantly reduce the number of required data samples that must be acquired, thereby reducing the radiation dose to patients. PICCS is based on standard compressed sensing L1-norm minimization techniques. An alternative homotopic L0-based minimization technique developed... Read More
2009-144 – Using audiovisual support we have created educational videos in all facets of General Surgery Education: Knot tying, Syringe, Specimen handling, Operative procedures, reading Chest X-rays/CT Scans/ MRI, etc. Basically we are creating a library of AV clips (30 seconds - 5 minutes) that educate Students/Residents/Fellows/Staff on everything in surgery.
WINCSWare: Two-way Wireless Communication Between Sensor and Control Unit for Data Aquisition and Selection of Sensing Parameters (Neurochemicals, Time, etc.) and Software for Processing of Incoming Data and Visual Display in Real-Time
2009-106 – Two-way Wireless Communication Between Sensor and Control Unit for Data Acquisition and Selection of Sensing Parameters (Neurochemicals, Time, etc.) and Software for Processing of Incoming Data and Visual Display in Real-Time.
Visual Syntactic Text Formatting to Improve Human Reading in Patient-Data Secure Electronic Health Systems
2009-089 – The invention combines computer-executed syntactic parsing algorithms with spatial layout parameters to reformat electronic text in cascading-phrase patterns that are designed to guide eye-movements, reduce visual regressions, and provide visual cues to sentence structure. Empirical studies, in both laboratory and real-world educational settings, have shown that this parser-generated format... Read More
2009-083 – MR Spectroscopy data is analyzed to yield high quality spectral images. Multiple acquisitions of MRS data are combines. The images are combined by time a phase shifting the data in the time domain (equivalent to interpolation) so that the data points all coincide on the same set of frequency points after fourier transforming. This avoids cancelation of the desired signal that would occur... Read More
2009-049 – Technology Description Due to the rapid increase in use of CT imaging and the recently-heightened awareness of radiation-induced cancer, improving the diagnostic quality of low dose CT has become increasingly important. The signal-to-noise level of low dose CT scans is significantly lower than for normal dose scans, and thus may cause a decrease in diagnostic accuracy. Mayo Clinic... Read More
2009-048 – Technology Description Intracranial aneurysms represent a difficult to detect cause of morbidity and mortality. Digital subtraction angiography is considered the gold standard for intracranial aneurysm detection, but this technique is associated with risk of neurologic complications. 3D time-of-flight magnetic resonance angiograpy (MRA) has recently emerged as a non- invasive screening... Read More
2009-047 – A complex set of gestures which, when performed using a screen pointer, facilitate fast and accurate selection of radial menu items from a radial menu.
2009-046 – A complex set of gestures which when performed using a screen pointer, facilitates fast and accurate selection of radial menu items from a radial menu.
2009-043 – To reduce radiation dose and/or improve image quality in CT, it is very important to select the optimal tube potential (kV), which is highly dependent on patient size and specific diagnostic task. In this invention, we developed a general strategy that allows for individualized automatic kV selection for each patient size and each diagnostic task. We proposed a novel concept, kV dose index... Read More
2008-386 – The use of ionizing radiation for diagnostic and interventional procedures has been growing at an exponential rate. The technical differences which exist among the sources of ionizing radiation are large - and necessitate computationally intensive and patient specific information in order to form a reasonable summary of an individual patient’s radiation dose. The invention specifies a... Read More
2008-294 – We have developed a method to assess the relative motion of various structures in the human carpal tunnel (tendon, nerve, and synovium) simultaneously using ultrasound We have also developed a method of comparing these motions by means of ratios and have shown that the ratios differ in normal individuals and those with carpal tunnel syndrome. The methods include both specific testing... Read More
2007-184 – In MR and CT imaging, any reduction in scan time offers potential benefits ranging from high temporal rate observation of physiologic processes to reduction of motion artifacts to lower radiation dose (for CT) to improved patient comfort and throughout. Following recent developments in compressive sensing theory, it has been shown that certain classes of MR imaging can be accurately... Read More
2007-154 – This invention is a technique that enables two or four port vector network analyzers (VNAs) to be probe-tip calibrated and used in applications such as automated test equipment . “Calibration” is understood to include a range of things described in more detail below. The technique complements (but is independent of) many industry¬wide standard probe-tip calibration methods such as... Read More
Rapid Electrical Link Analysis Technique for Simulating Electrical Signals Through Transmission Media Characterized by Scattering Parameters
2007-135 – This technique is a software program which permits very rapid simulation of electrical signals through passive transmission or any other interconnect characterized by scattering parameters (S-parameters). An unlimited number of 2-port and 4-port passive interconnect models are combined into a single interconnect using proper S-parameter cascading. External transient voltage waveforms... Read More
2007-129 – Material-specific removal of image signal using dual-energy CT subtraction paradigms has the undesirable effect of altering signal throughout the image while increasing image noise. This novel algorithm preselects the material of interest and performs the dual-energy subtraction process only on those voxels meeting certain criteria. In this manner, material-specific subtraction is... Read More
2007-009 – Currently, radiologists interpreting CT colonography exams find it most efficient to view colons primarily in a 2D axial mode, scrolling these slices up and down the abdomen. Typically, the entire colon is scanned twice on the computer screen, first with a “lung” window/level setting (analogous to contrast/brightness) that clearly shows protrusions into the lumen and identifies most typical... Read More
2007-008 – CT colonography (CTC) is being extensively studied for its potential value in colon examinations. Like traditional colonoscopy, CTC requires extensive preparation to cleanse the colon of fecal material. The inconvenience and discomfort associated with this preparation is an important obstacle to compliance with currently recommended colorectal screening guidelines. An alternative is to tag... Read More
2007-007 – This invention consists of a novel display technique for CT colonography data. It is based on automatic generation of a midline trace (centerline) of the colon, followed by display of a sequence of images of the colon that follow this centerline, and display a small field of view centered on it and perpendicular to it. This allows the radiologist the benefit of always seeing the colon in... Read More
2007-006 – This invention consists of a novel display technique for CT colonography data. It is based on automatic generation of a midline trace (centerline) of the colon, followed by display of a sequence of axial images that display a small field of view centered on the trace, and follow along it. This allows the radiologist the benefit of a small field of view to examine the image, but frees him from... Read More
2006-259 – The algorithm automatically generates samples of key tissues from magnetic resonance brain images.
2006-196 – The MR shell k-space trajectory is a way to acquire MRI data. It has several intrinsic advantages over standard methods, including improved acquisition efficiency per unit time, compatibility with motion correction methods, and a high degree of venous suppression when used to acquire contrast-enhanced MR angiograms of arteries with intravenous injection of gadolinium-chelate contrast agents.... Read More
2005-022 – CT colonography (CTC) offers advantages for colon examinations such as lower risk and less patient discomfort. However, CTC requires complete bowel preparation (cleansing). The inconvenience and discomfort of this process greatly reduces patient compliance and is a major obstacle to widespread colorectal screening. An alternative is to tag the stool with an opacifying agent so that it is... Read More
2004-231 – The present invention details a substantial implementation improvement for a broad class of Direct Digital Synthesizers (DDSs). A DDS synthesizes a predetermined waveform via digital (i.e., sampled) methods. Typically, the output waveforms are based on sinusoidal functions. For example, a DDS may generate sine waves of various frequency (under digital control). Chirp waveforms (which are... Read More
2004-194 – Invention represents ARMA model describing dynamic behavior between QT and RR intervals in ECG signal. Model predicts QT behavior from detected RR changes. Parameters of model seem to be identical for healthy subjects in all age groups and for both genders. Model may be applied for better understanding of QT interval regulation physiology and pathophysiology, individual sudden arrhythmic... Read More
2004-085 – Tissue engineering scaffolds are biomimetic “trellis-like” structures which, on implantation and integration, act as tissue/organ surrogates. This disclosure enables the construction of multi-resolution, variably-refineable, globally interconnected, monolithic and maximally porous scaffolds.
2004-084 – Tissue engineering attempts to address the widening gap between the demand and supply of organ and tissue transplants using natural and biomimetic scaffolds. This invention provides a method to enable the repeatable and rapid fabrication of structurally and functionally enhanced and maximally characterized traditional scaffolds.
2004-056 – This disclosure provides a way to improve the Talairach Labeling scheme that allows labelings to be reported at 0.2 mm resolution - providing 2500% increase over the current standard.
2004-055 – This invention performs a robust, fast and fully automatic parameterization of T2 images into an intensity space that all existing approaches optimized to handle T1 images can benefit from.
2004-027 – To accomplish a given computational task, a number of algorithmic and heuristic approaches can be implemented to act upon the given instance of the input data. Depending upon the intrinsic and extrinsic assumptions made regarding the data, algorithm and the task, the end result from each of these approaches could be different. Currently, there does not exist an automatic fast, robust, precise... Read More
Prior Knowledge-Based Rapid Predicted Preview of Multiple Contrast Magnetic Resonance Images Derived from a Single Time Budgeted Acquisition
2004-023 – This invention presents a method for producing multiple MR images with different contrast from a single image acquisition. (MR T2) The methodology is used to enhance the T2 related contrast in an MRI image acquired at, but no restricted to, just-enough-to-highlight-T2, repetition time so as to produce a computed mosaic of the same image at different repetition (TR) and echo (TE) times. This... Read More
2004-020 – The CCAP program accurately and efficiently counts and analyzes cells in microscope images. A user interactively completes the followings steps: 1) Inhomogeneity correction: A digital filter is applied to correct for uneven illumination. 2) Calibration: A line is placed over an object of known size, usually a ruler, to determine the size of the image pixels. 3) Segmentation: The cells... Read More
Projection Angle Order and Correction Algorithm to Compensate In-Plane Rotation and Translation in Radial MRI Scans
2004-008 – The motion correction strategy compensates for rigid-body in-plane rotation and translation of the imaged object by collecting radial MRI data with a novel projection view angle acquisition order followed by a data correction algorithm. A custom MR pulse sequence was created to collect radial projections with a consistent spacing of approximately 45 degrees, which is crucial for the novel... Read More
2002-025 – Computer software which locates polyps and cancers of the colon on CT colonography data sets.
2001-160 – A common problem in clinical magnetic resonance imaging is misalignment of the individual imaging slices on sequential patient examinations. This inter-image misregistration frequently confounds accurate assignment of change or lack thereof in pathologic lesions across serial studies. We describe a rapid and accurate method to register the individual slices of MR images obtained at... Read More
2001-069 – Rigid body translations of an object in MRI will create image artifacts along the phase enclode (PE) direction in standard 2DFT imaging. If two images are acquired with swapped PE direction, it is theoretically possible to determine and correct for arbitrary translational motions in both images directly from the phase differences in the k-space acquisitions by solving a large system of... Read More
2001-042 – MR based technique for accurately detecting seed locations following prostate brachytherapy seed therapy. This method optimizes phase perturbations introduced into prostate and surrounding tissue resulting from implantation of brachytherapy seeds with differing susceptibility values and can accurately determine seed location and orientation in the prosstate and surrounding tissue.
2001-001 – Nearly all elderly persons develop pathologic areas of cell loss and demyelination (called leukoaraiosis), in the central areas of the brain. We have developed an accurate and highly reproducible method for quantitatively measuring the volume of leukoaraiosis from a magnetic resonance image of the brain.
2000-131 – An interactive software interface to a detailed brain atlas developed by Kent Ridge Digital Laboratories in Singapore which permits access, display and manipulation of the atlas within the analyze software system. The interface permits rapid and accurate registration of the brain atlas to MRI scans of the brain for the purpose of labeling, segmentation or other functions where defined and... Read More
2000-037 – A 3D motion adjustment pulse sequence is interleaved with magnetic resonance image (MRI) acquisition. This motion adjustment pulse sequence encodes all six degrees of rigid body motion in a single 3D spherical k-space dataset and is used to measure patient motion during the scan. The MRI system’s scan parameters are prospectively adjusted during the scan to offset the effects of patient... Read More
2000-013 – The development of a delivery mechanism (pill or capsule) for barium sulfate which is used for the purpose of altering the density of stool sufficiently that it can be electronically subtracted. A new software tool (computer algorithm) for electronic subtraction of contrast-laden stool has been developed.
1999-036 – AVWPC is a comprehensive set of imaging functions which facilitates full exploration and analysis of multidimensional, multimodality biomedical image data sets that runs on PCs using C compilers and operating systems such as Windows. The software also facilitates the development and implementation of advanced imaging algorithms and techniques and easy integration of these into specific... Read More
1997-109 – System for clinical image display.
1995-055 – Imaging of Tubular Structures; Systems and methods have been developed for imaging tubular structures in the body using 2D and/or 3D.
1994-101 – Technology Description Hospitals and surgery centers face significant cost pressure when it comes to maintaining materials and supplies. With supply costs representing a significant expense in surgical services, close and careful monitoring is needed to reduce costs and improve efficiencies. Developed at Mayo Clinic, the Supply Inventory Management System (SIMS) is a comprehensive program... Read More